Publications

Kira Breunig, Xiufen Lei, Mauro Montalbano, Gabriela D A Guardia, Shiva Ostadrahimi, Victoria Alers, Adam Kosti, Jennifer Chiou, Nicole Klein, Corina Vinarov, Lily Wang, Mujia Li, Weidan Song, W Lee Kraus, David S Libich, Stefano Tiziani, Susan T Weintraub, Pedro A F Galante, Luiz O F Penalva. SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis. eLIFe. 2024 PubMed PMID: 38585848

Maria Virginia Giolito, Serguei Bodoirat, Theo La Rosa, Mathieu Reslinger, Gabriela D A Guardia, Jana Mourtada, Leo Claret, Alain Joung, Pedro A F Galante, Luiz O F Penalva, Michelina Plateroti. Impact of the thyroid hormone T3 and its nuclear receptor TRα1 on colon cancer stem cell phenotypes and response to chemotherapies. Cell Death & Disease . 2024 PubMed PMID: 38693105

Daniela Moreira Mombach, Rafael Luiz Vieira Mercuri, Tiago Minuzzi Freire da Fontoura Gomes, Pedro A F Galante, Elgion Lucio Silva Loreto. Transposable elements alter gene expression and may impact response to cisplatin therapy in ovarian cancer. Carcinogenesis. 2024 PubMed PMID: 38722203

Mariana dos Santos Oliveira, Marcelo de C Griebeler, Bernardo Henz, Filipe Ferreira dos Santos, Gabriela D A Guardia, Helena B Conceição, Pedro A F Galante, Darlan C Minussi, Manuel M Oliveira, Guido Lenz. Population Dynamics is a Cancer Driver. Carcinogenesis. 2024 PubMed PMID: 38842162

Anelisa Gollo Dantas, Beatriz Carvalho Nunes, Natália Nunes, Pedro Galante, Paula Fontes Asprino, Vanessa Kiyomi Ota & Maria Isabel Melaragno. Next-generation sequencing profiling of miRNAs in individuals with 22q11.2 deletion syndrome revealed altered expression of miR-185-5p. Human Genomics. 2024 PubMed PMID: 38872198

Ana Maria Rodrigues, Ana Paula Zen Petisco Fiore, Gabriela D. A. Guardia, Rebeka Tomasin, André Azevedo Reis Teixeira, Ricardo Jose Giordano, Deborah Schechtman, Michele Pagano, Pedro A. F. Galante & Alexandre Bruni-Cardoso. Identification of a novel alternative splicing isoform of the Hippo kinase STK3/MST2 with impaired kinase and cell growth suppressing activities. Oncogene. 2024 PubMed PMID: 39174858

Helena B Conceição, Rafael L V Mercuri, Matheus P M de Castro, Daniel T Ohara, Gabriela D A Guardia, Pedro A F Galante. RCPedia: a global resource for studying and exploring retrocopies in diverse species. Bioinformatics. 2024 PubMed PMID: 39240653

Raquel Martinez Ramos, Reginaldo José Petroli, Nathália Da Roz D' Alessandre, Gabriela Der Agopian Guardia, Ana Caroline de Freitas Afonso, Mirian Yumie Nishi, Sorahia Domenice, Pedro Alexandre Favoretto Galante, Berenice Bilharinho Mendonca, Rafael Loch Batista. Small Indels in the Androgen Receptor Gene: Phenotype Implications and Mechanisms of Mutagenesis. J Clin Endocrinol Metab. 2023 PubMed PMID: 37572362

Kosti A, Chiou J, Guardia GDA, Lei X, Balinda H, Landry T, Lu X, Qiao M, Gilbert A, Brenner A, Galante PAF, Tiziani S, Penalva LOF.. ELF4 is a critical component of a miRNA-transcription factor network and is a bridge regulator of glioblastoma receptor signaling and lipid dynamics. Neuro Oncology. 2023 PubMed PMID: 35862252

Rocha BGS, Picoli CC, Gonçalves BOP, Silva WN, Costa AC, Moraes MM, Costa PAC, Santos GSP, Almeida MR, Silva LM, Singh Y, Falchetti M, Guardia GDA, Guimarães PPG, Russo RC, Resende RR, Pinto MCX, Amorim JH, Azevedo VAC, Kanashiro A, Nakaya HI, Rocha EL, Galante PAF, Mintz A, Frenette PS, Birbrair A.. Tissue-resident glial cells associate with tumoral vasculature and promote cancer progression.. Angiogenesis. 2023 PubMed PMID: 36183032

Xavier CB, Link R, Abreu L, Bettoni F, Marson F, Galante PAF, Masotti C, Amano MT, de Molla V, Camargo AA, Asprino PF, Sabbaga J.. Suspected Germline TP53 Variants and Clonal Hematopoiesis of Indeterminate Potential: Lessons Learned From a Molecular Tumor Board. Oncologist.. 2023 PubMed PMID: 37159554

Corradi C, Vilar JB, Buzatto VC, de Souza TA, Castro LP, Munford V, De Vecchi R, Galante PAF, Orpinelli F, Miller TLA, Buzzo JL, Sotto MN, Saldiva P, de Oliveira JW, Chaibub SCW, Sarasin A, Menck CFM. . Mutational signatures and increased retrotransposon insertions in xeroderma pigmentosum variant skin tumors. . Carcinogenesis.. 2023 PubMed PMID: 37195263

Barreiro RAS, Guardia GDA, Meliso FM, Lei X, Li WQ, Savio A, Fellermeyer M, Conceição HB, Mercuri RLV, Landry T, Qiao M, Blazquez L, Ule J, Penalva LOF, Galante PAF. . The paralogues MAGOH and MAGOHB are oncogenic factors in high-grade gliomas and safeguard the splicing of cell division and cell cycle genes. . RNA Biology. 2023 PubMed PMID: 37294214

Guardia GDA, Naressi RG, Buzzato VC, da Costa JB, Zalcberg I, Ramires J, Malnic B, Gutiyama LM, Galante PAF. . Acute Myeloid Leukemia Expresses a Specific Group of Olfactory Receptors.. Cancers. 2023 PubMed PMID: 37370684

Rangel-Pozzo A, Dos Santos FF, Dettori T, Giulietti M, Frau DV, Galante PAF, Vanni R, Pathak A, Fischer G, Gartner J, Caria P, Mai S. . Three-dimensional nuclear architecture distinguishes thyroid cancer histotypes.. Int J Cancer.. 2023 PubMed PMID: 37539710

Luis Eduardo Barbalho de Mello, Thaise Nayane Ribeiro Carneiro, Aline Neves Araujo, Camila Xavier Alves, Pedro Alexandre Favoretto Galante, Vanessa Candiotti Buzatto, Maria das Graças de Almeida, Karina Marques Vermeulen-Serpa, Sancha Helena de Lima Vale, Fernando José de Pinto Paiva, José Brandão-Neto, Janete Maria Cerutti. Identification of NID1 as a novel candidate susceptibility gene for familial non-medullary thyroid carcinoma using whole-exome sequencing. Endocrine Connections. 2022 PubMed PMID: 34941562

Michel S Naslavsky, Marilia O Scliar, Guilherme L Yamamoto, Jaqueline Yu Ting Wang, Stepanka Zverinova, Tatiana Karp, Kelly Nunes, José Ricardo Magliocco Ceroni, Diego Lima de Carvalho, Carlos Eduardo da Silva Simões, Daniel Bozoklian, Ricardo Nonaka, Nayane Dos Santos Brito Silva, Andreia da Silva Souza, Heloísa de Souza Andrade, Marília Rodrigues Silva Passos, Camila Ferreira Bannwart Castro, Celso T Mendes-Junior, Rafael L V Mercuri, Thiago L A Miller, Jose Leonel Buzzo, Fernanda O Rego, Nathalia M Araújo, Wagner C S Magalhães, Regina Célia Mingroni-Netto, Victor Borda, Heinner Guio, Carlos P Rojas, Cesar Sanchez, Omar Caceres, Michael Dean, Mauricio L Barreto, Maria Fernanda Lima-Costa, Bernardo L Horta, Eduardo Tarazona-Santos, Diogo Meyer, Pedro A F Galante, Victor Guryev, Erick C Castelli, Yeda A O Duarte, Maria Rita Passos-Bueno, Mayana Zatz. Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil. Nature Communications. 2022 PubMed PMID: 35354829

Rodrigo Araujo Sequeira Barreiro, Jorge Sabbaga, Benedito M Rossi, Maria Isabel W Achatz, Fabiana Bettoni, Anamaria A Camargo, Paula F Asprino, Pedro A F Galante. Monoallelic deleterious MUTYH germline variants as a driver for tumorigenesis. The Journal of Pathology. 2022 PubMed PMID: 34816434

Anacleto Silva de Souza, Vitor Martins de Freitas Amorim, Gabriela D A Guardia, Filipe F Dos Santos, Henning Ulrich, Pedro A F Galante, Robson Francisco de Souza, Cristiane Rodrigues Guzzo. Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern: A Perspective for Emerging More Transmissible and Vaccine-Resistant Strains. Viruses. 2022 PubMed PMID: 35458557

Adam Kosti, Jennifer Chiou, Gabriela D A Guardia, Xiufen Lei, Henriette Balinda, Tesha Landry, Xiyuan Lu, Mei Qiao, Andrea Gilbert, Andrew Brenner, Pedro A F Galante, Stefano Tiziani, Luiz O F Penalva. ELF4 is a critical component of a miRNA-transcription factor network and is a bridge regulator of glioblastoma receptor signaling and lipid dynamics. Neuro-Oncology. 2022 PubMed PMID: 35862252

Alex Ranieri Jerônimo Lima, Herbert Guimarães de Sousa Silva, Saloe Poubel, Juliana Nunes Rosón, Loyze Paola Oliveira de Lima, Héllida Marina Costa-Silva, Camila Silva Gonçalves, Pedro A F Galante, Fabiola Holetz, Maria Cristina Machado Motta, Ariel M Silber, M Carolina Elias, Julia Pinheiro Chagas da Cunha. Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci. Epigenetics & Chromatin. 2022 PubMed PMID: 35650626

Anacleto Silva de Souza, Vitor Martins de Freitas Amorim, Gabriela D A Guardia, Felipe R C Dos Santos, Filipe F Dos Santos, Robson Francisco de Souza, Guilherme de Araujo Juvenal, Yihua Huang, Pingju Ge, Yinan Jiang, Coco Li, Prajwal Paudel, Henning Ulrich, Pedro A F Galante, Cristiane Rodrigues Guzzo . Molecular Dynamics Analysis of Fast-Spreading Severe Acute Respiratory Syndrome Coronavirus 2 Variants and Their Effects on the Interaction with Human Angiotensin-Converting Enzyme 2. ACS Omega. 2022 PubMed PMID: 36068861

Camila B Xavier, Carlos Diego H Lopes, Beatriz M Awni, Eduardo F Campos, João Pedro B Alves, Anamaria A Camargo, Gabriela D A Guardia, Pedro A F Galante, Denis L Jardim. Interplay between Tumor Mutational Burden and Mutational Profile and Its Effect on Overall Survival: A Pilot Study of Metastatic Patients Treated with Immune Checkpoint Inhibitors. Cancers. 2022 PubMed PMID: 36358851

Maria Virginia Giolito, Théo La Rosa, Diana Farhat, Serguei Bodoirat, Gabriela D A Guardia, Claire Domon-Dell, Pedro A F Galante, Jean-Noel Freund, Michelina Plateroti. Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions. Molecular Oncology. 2022 PubMed PMID: 36217307

Thiago L A Miller, Fernanda Orpinelli, José Leonel L Buzzo, Pedro A F Galante. sideRETRO: a pipeline for identifying somatic and polymorphic insertions of processed pseudogenes or retrocopies. Bioinformatics. 2021 PubMed PMID: 32717039

Adam Kosti, Rodrigo Barreiro, Gabriela D A Guardia, Shiva Ostadrahimi, Erzsebet Kokovay, Alexander Pertsemlidis, Pedro A F Galante, Luiz O F Penalva. Synergism of Proneurogenic miRNAs Provides a More Effective Strategy to Target Glioma Stem Cells. Cancers. 2021 PubMed PMID: 33466745

Pedro A C Costa, Walison N Silva, Pedro H D M Prazeres, Caroline C Picoli, Gabriela D A Guardia, Alinne C Costa, Mariana A Oliveira, Pedro P G Guimarães, Ricardo Gonçalves, Mauro C X Pinto, Jaime H Amorim, Vasco A C Azevedo, Rodrigo R Resende, Remo C Russo, Thiago M Cunha, Pedro A F Galante, Akiva Mintz, Alexander Birbrair. Chemogenetic modulation of sensory neurons reveals their regulating role in melanoma progression. Acta Neuropathologica Communications. 2021 PubMed PMID: 34784974

Larissa Valdemarin Bim, Thaise Nayane Ribeiro Carneiro, Vanessa Candiotti Buzatto, Gabriel Avelar Colozza-Gama, Fernanda C Koyama, Debora Mota Dias Thomaz, Ana Carolina de Jesus Paniza, Eunjung Alice Lee, Pedro Alexandre Favoretto Galante, Janete Maria Cerutti. Molecular Signature Expands the Landscape of Driver Negative Thyroid Cancers. Cancers. 2021 PubMed PMID: 34680332

Carla Frau, Catherine Jamard, Gaspard Delpouve, Gabriela D A Guardia, Christelle Machon, Camilla Pilati, Clémentine Le Nevé, Pierre Laurent-Puig, Jérôme Guitton, Pedro A F Galante, Luiz O Penalva, Jean-Noel Freund, Christelle de la Fouchardiere, Michelina Plateroti. Deciphering the Role of Intestinal Crypt Cell Populations in Resistance to Chemotherapy. Cancer Research. 2021 PubMed PMID: 33741693

Thaise Nayane Ribeiro Carneiro, Larissa Valdemarin Bim, Vanessa Candiotti Buzatto, Vanessa Galdeno, Paula Fontes Asprino, Eunjung Alice Lee, Pedro Alexandre Favoretto Galante, Janete Maria Cerutti. Evidence of Cooperation between Hippo Pathway and RAS Mutation in Thyroid Carcinomas. Cancers. 2021 PubMed PMID: 34065786

Felipe R C Dos Santos, Gabriela D A Guardia, Filipe F Dos Santos, Daniel T Ohara, Pedro A F Galante. Reboot: a straightforward approach to identify genes and splicing isoforms associated with cancer patient prognosis. NAR Cancer. 2021 PubMed PMID: 34316711

Mirella Baroni, Gabriela D A Guardia, Xiufen Lei, Adam Kosti, Mei Qiao, Tesha Landry, Karl Mau, Pedro A F Galante, Luiz O F Penalva. The RNA-Binding Protein Musashi1 Regulates a Network of Cell Cycle Genes in Group 4 Medulloblastoma. Cells. 2021 PubMed PMID: 35011618

Maíra H Nagai, Victor P S Xavier, Luciana M Gutiyama, Cleiton F Machado, Alice H Reis, Elisa R Donnard, Pedro A F Galante, Jose G Abreu, William T Festuccia, Bettina Malnic. Depletion of Ric-8B Leads to Reduced mTORC2 Activity. PLOS GENETICS. 2020 PubMed PMID: 32392211

K M Santiago, L P Castro, J P D Neto, A F de Nóbrega, C A L Pinto, P Ashton-Prolla, F Pinto E Vairo, P F V de Medeiros, E M Ribeiro, B F R Ribeiro, F F do Valle, M J R Doriqui, C H B Leite, R M Rocha, L M S Moura, V Munford, P A F Galante, C F M Menck, S R Rogatto, M I Achatz. Comprehensive Germline Mutation Analysis and Clinical Profile in a Large Cohort of Brazilian Xeroderma Pigmentosum Patients. Journal of the European Academy of Dermatology and Venereology. 2020 PubMed PMID: 32239545

Vanessa Kiyomi Ota, Marcos Leite Santoro, Leticia Maria Spindola, Pedro Mario Pan, Andressa Simabucuro, Gabriela Xavier, Tamiris Vieira-Fonseca, Evelin Aline Zanardo, Felipe Rodolfo Camargo dos Santos, Julia Luiza Schäfer, Leslie Domenici Kulikowski, Pedro A. F. Galante, Paula Fontes Asprino, Elisa Brietzke, Rodrigo Grassi-Oliveira, Luis Augusto Rohde, Euripedes Constantino Miguel, Ary Gadelha, Jair Jesus Mari, Rodrigo Affonseca Bressan, Giovanni Abrahao Salum & Sintia Iole Belangero. Gene expression changes associated with trajectories of psychopathology in a longitudinal cohort of children and adolescents. Translational Psychiatry. 2020 PubMed PMID: 32184383

Gabriela D. A. Guardia, Bruna R. Correa, Patricia Rosa Araujo, Mei Qiao, Suzanne Burns, Luiz O. F. Penalva and Pedro A. F. Galante. Proneural and Mesenchymal Glioma Stem Cells Display Major Differences in Splicing and lncRNA Profiles. NPJ Genomic Medicine. 2020 PubMed PMID: 31969990

Rubens Daniel Miserani Magalhães, Eliciane Cevolani Mattos, Andrei Rozanski, Pedro Alexandre Favoretto Galante, Giuseppe Palmisano, Angela Kaysel Cruz, Walter Colli, Anamaria Aranha Camargo, Maria Júlia Manso Alves. Global changes in nitration levels and DNA binding profile of Trypanosoma cruzi histones induced by incubation with host extracellular matrix. PLOS Neglected Tropical Diseases. 2020 PubMed PMID: 32469928

Adam Kosti, Patricia Rosa de Araujo, Wei-Qing Li, Gabriela D A Guardia, Jennifer Chiou, Caihong Yi, Debashish Ray, Fabiana Meliso, Yi-Ming Li, Talia Delambre, Mei Qiao, Suzanne S Burns, Franziska K Lorbeer, Fanny Georgi, Markus Flosbach, Sarah Klinnert, Anne Jenseit, Xiufen Lei, Carolina Romero Sandoval, Kevin Ha, Hong Zheng, Renu Pandey, Aleksandra Gruslova, Yogesh K Gupta, Andrew Brenner, Erzsebet Kokovay, Timothy R Hughes, Quaid D Morris, Pedro A F Galante, Stefano Tiziani, Luiz O F Penalva. The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation. Genome Biology. 2020 PubMed PMID: 32762776

Tábatha de Oliveira Silva, Caroline A Lino, Vanessa C Buzatto, Paula Fontes Asprino, Yao Wei Lu, Vanessa M Lima, Renata I B Fonseca, Leonardo Jensen, Gilson M Murata, Sidney V Filho, Márcio A C Ribeiro, Jose Jr Donato, Julio C B Ferreira, Alice C Rodrigues, Maria Cláudia Irigoyen, Maria Luiza M Barreto-Chaves, Zhan-Peng Huang, Pedro A Favoretto Galante, Da-Zhi Wang, Gabriela P Diniz. Deletion of miRNA-22 Induces Cardiac Hypertrophy in Females but Attenuates Obesogenic Diet-Mediated Metabolic Disorders. Cellular Physiology & Biochemistry. 2020 PubMed PMID: 33252886

Fabiana Bettoni, Cibele Masotti, Bruna R. Corrêa, Elisa Donnard, Filipe F. dos Santos, Guilherme P. São Julião, Bruna B. Vailati, Angelita Habr-Gama, Pedro A. F. Galante, Rodrigo O. Perez and Anamaria A. Camargo. The Effects of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer—The Impact in Intratumoral Heterogeneity. Frontiers in Oncology. 2019 PubMed PMID: 31612112

Antonio P Camargo, Thiago S Nakahara, Luiz E R Firmino, Paulo H M Netto, João B P do Nascimento, Elisa R Donnard, Pedro A F Galante, Marcelo F Carazzolle, Bettina Malnic, Fabio Papes. Uncovering the mouse olfactory long non-coding transcriptome with a novel machine-learning model.. DNA Research. 2019 PubMed PMID: 31321403

Larissa V. Bim, Fábio C. P. Navarro, Flávia O. F. Valente, José V. Lima-Junior, Rosana Delcelo, Magnus R. Dias-da-Silva, Rui M. B. Maciel, Pedro A. F. Galante & Janete M. Cerutti. Retroposed copies of RET gene: a somatically acquired event in medullary thyroid carcinoma. BMC Medical Genomics. 2019 PubMed PMID: 31288802

Mitzli X. Velasco, Adam Kosti, Gabriela D. A. Guardia, Marcia C. Santos, Allison Tegge, Mei Qiao, Bruna R. S. Correa, Greco Hernandez, Erzsebet Kokovay, Pedro A. F. Galante, Luiz O. F. Penalva. Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development.. RNA. 2019 PubMed PMID: 31004009

Jared P. Steranka, Zuojian Tang, Mark Grivainis, Cheng Ran Lisa Huang, Lindsay M. Payer, Fernanda O. R. Rego, Thiago Luiz Araujo Miller, Pedro A. F. Galante, Sitharam Ramaswami, Adriana Heguy, David Fenyö, Jef D. Boeke & Kathleen H. Burns. Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome.. Mobile DNA. 2019 PubMed PMID: 30899333

Bruna RS Correa, Joanna Hu, Luiz OF Penalva, Richard Schlegel, David L Rimm, Pedro AF Galante, Seema Agarwal. Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity. Scientific reports. 2018 PubMed PMID: 29511269

Paula Fontes Asprino, Rudinei Diogo Marques Linck, Jônatas Cesar, Florêncio Porto Freitas, Fernanda Christtanini Koyama, Rachel Simões Pimenta Riechelmann, Frederico Perego Costa, Paulo Marcelo Gehm Hoff, Pedro Alexandre Favoretto Galante, Diogo Meyer, Anamaria Aranha Camargo, Jorge Sabbaga. TSC2 rare germline variants in non-tuberous sclerosis patients with neuroendocrine neoplasias. Endocrine-related cancer. 2018 PubMed PMID: 29167182

Marcia Cristina T dos Santos, Miguel Arturo Barreto-Sanz, Bruna Renata S Correia, Rosie Bell, Catherine Widnall, Luis Tosar Perez, Caroline Berteau, Claudia Schulte, Dieter Scheller, Daniela Berg, Walter Maetzler, Pedro AF Galante, Andre Nogueira da Costa. miRNA-based signatures in cerebrospinal fluid as potential diagnostic tools for early stage Parkinson’s disease. Oncotarget. 2018 PubMed PMID: 29707120

Max Hübner, Pedro AF Galante, Simone Kreth, Ludwig Christian Hinske. Identification and Validation of Potential Differential miRNA Regulation via Alternative Polyadenylation. MicroRNA Protocols. 2018 PubMed PMID: 29435925

Rosalinda Yasato Camargo, Cristina Takami Kanamura, Celso Ubirajara Friguglietti, Célia Regina Nogueira, Sonia Iorcansky, Alfio José Tincani, Ana Karina Bezerra, Ester Brust, Fernanda Christtanini Koyama, Anamaria Aranha Camargo, Fernanda Orpinelli R Rego, Pedro Alexandre Favoretto Galante, Geraldo Medeiros-Neto, Ileana Gabriela Sanchez Rubio. Histopathological Characterization and Whole Exome Sequencing of Ectopic Thyroid: Fetal Architecture in a Functional Ectopic Gland from Adult Patient. International journal of endocrinology. 2018 PubMed PMID: 29593791

C Masotti, LA Brito, AC Nica, KU Ludwig, K Nunes, CP Savastano, C Malcher, SG Ferreira, GS Kobayashi, DF Bueno, N Alonso, D Franco, A Rojas-Martinez, SE Dos Santos, PA Galante, D Meyer, T Hünemeier, E Mangold, ET Dermitzakis, MR Passos-Bueno. MRPL53, a New Candidate Gene for Orofacial Clefting, Identified Using an eQTL Approach. Journal of dental research. 2018 PubMed PMID: 29053389

Fabiana Bettoni, Cibele Masotti, Angelita Habr-Gama, Bruna R Correa, Joaquim Gama-Rodrigues, Maria R Vianna, Bruna B Vailati, Guilherme P São Julião, Laura M Fernandez, Pedro A Galante, Anamaria A Camargo, Rodrigo O Perez. Intratumoral Genetic Heterogeneity in Rectal Cancer: Are Single Biopsies representative of the entirety of the tumor?. Annals of surgery. 2017 PubMed PMID: 27479130

Munford V, Castro LP, Souto R, Lerner LK, Vilar JB, Quayle C, Asif H, Schuch AP, de Souza TA, Ienne S, Alves FI, Moura LM, Galante PA, Camargo AA, Liboredo R, Pena SD, Sarasin A, Chaibub SC, Menck CF. A genetic cluster of xeroderma pigmentosum variant patients with two different founder mutations. Br J Dermatol. 2017 PubMed PMID: 27664908

Ludwig C Hinske, Felipe RC dos Santos, Daniel T Ohara, Lucila Ohno-Machado, Simone Kreth, Pedro AF Galante. MiRIAD update: using alternative polyadenylation, protein interaction network analysis and additional species to enhance exploration of the role of intragenic miRNAs and their host genes.. Database. 2017 PubMed PMID: 29220447

Gustavo S França, Ludwig C Hinske, Pedro AF Galante, Maria D Vibranovski. Unveiling the Impact of the Genomic Architecture on the Evolution of Vertebrate microRNAs. Frontiers in genetics. 2017 PubMed PMID: 28377786

Luis Felipe Campesato, Ana Paula M Silva, Luna Cordeiro, Bruna R Correa, Fabio CP Navarro, Rafael F Zanin, Marina Marçola, Lilian T Inoue, Mariana L Duarte, Martina Molgora, Fabio Pasqualini, Matteo Massara, Pedro Galante, Romualdo Barroso-Sousa, Nadia Polentarutti, Federica Riva, Erico T Costa, Alberto Mantovani, Cecilia Garlanda, Anamaria A Camargo. High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity. Oncotarget. 2017 PubMed PMID: 28533483

Fabiana Marcelino Meliso, Christopher G Hubert, Pedro A Favoretto Galante, Luiz O Penalva. RNA processing as an alternative route to attack glioblastoma. Human genetics. 2017 PubMed PMID: 28608251

Julia Alejandra Pezuk, Thiago Luiz Araujo Miller, José Luiz Barbosa Bevilacqua, Alfredo Carlos Simões Dornellas de Barros, Felipe Eduardo Martins de Andrade, Luiza Freire de Andrade e Macedo, Vera Aguilar, Amanda Natasha Menardo Claro, Anamaria Aranha Camargo, Pedro Alexandre Favoretto Galante, Luiz FL Reis. Measuring plasma levels of three microRNAs can improve the accuracy for identification of malignant breast lesions in women with BI-RADS 4 mammography. Oncotarget. 2017 PubMed PMID: 29137394

Fabiana Bettoni, Fernanda Christtanini Koyama, Paola de Avelar Carpinetti, Pedro Alexandre Favoretto Galante, Anamaria Aranha Camargo, Paula Fontes Asprino. A straightforward assay to evaluate DNA integrity and optimize next-generation sequencing for clinical diagnosis in oncology. Experimental and molecular pathology. 2017 PubMed PMID: 29175301

Correa BR, de Araujo PR, Qiao M, Burns SC, Chen C, Schlegel R, Agarwal S, Galante PA, Penalva LO. Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma. Genome Biol. 2016 PubMed PMID: 27287018

França GS, Vibranovski MD, Galante PA. Host gene constraints and genomic context impact the expression and evolution of human microRNAs. Nat Commun. 2016 PubMed PMID: 27109497

Nagai Maira, LM Gutiyama, CF Machado, PAF Galante, B Malnic. Ric-8B, an olfactory GEF, is essential for the development of the nervous system.. CHEMICAL SENSES. 2016 PubMed PMID:

Elaine Castilho Guedes, Gustavo Starvaggi França, Caroline Antunes Lino, Fernanda Christtanini Koyama, Luana do Nascimento Moreira, Juliana Gomes Alexandre, Maria Luiza M Barreto‐Chaves, Pedro Alexandre Favoretto Galante, Gabriela Placoná Diniz. MicroRNA expression signature is altered in the cardiac remodeling induced by high fat diets. Journal of cellular physiology. 2016 PubMed PMID: 26638879

Wânia Rezende Lima, Giulliana Tessarin-Almeida, Andrei Rozanski, Kleber S Parreira, Miriam S Moraes, David C Martins, Ronaldo F Hashimoto, Pedro AF Galante, Célia RS Garcia. Signaling transcript profile of the asexual intraerythrocytic development cycle of Plasmodium falciparum induced by melatonin and cAMP. Genes & cancer. 2016 PubMed PMID: 28050233

RDM Linck, PF Asprino, FP Freitas, FC Koyama, PAF Galante, R Riechelmann, LFL Reis, FP Costa, PM Hoff, AA Camargo, J Sabbaga. Damaging germline variants in TSC2 are frequently found among nonsyndromic patients with gastroenteropancreatic (GEP) neuroendocrine tumors (NETs). Annals of Oncology. 2016 PubMed PMID:

Daniela C Gonzalez-Kristeller, João BP do Nascimento, Pedro AF Galante, Bettina Malnic. Identification of agonists for a group of human odorant receptors. Frontiers in pharmacology. 2015 PubMed PMID: 25784876

Ludwig Christian Hinske, Pedro AF Galante, Elisabeth Limbeck, Patrick Möhnle, Raphael B Parmigiani, Lucila Ohno-Machado, Anamaria A Camargo, Simone Kreth. Alternative polyadenylation allows differential negative feedback of human miRNA miR-579 on its host gene ZFR. PloS one. 2015 PubMed PMID: 25799583

Elisa R Donnard, Paola A Carpinetti, Fábio CP Navarro, Rodrigo O Perez, Angelita Habr-Gama, Raphael B Parmigiani, Anamaria A Camargo, Pedro AF Galante. ICRmax: an optimized approach to detect tumor-specific interchromosomal rearrangements for clinical application. Genomics. 2015 PubMed PMID: 25666663

Camila Lopes-Ramos, Fernanda C Koyama, Angelita Habr-Gama, Anna Christina M Salim, Fabiana Bettoni, Paula F Asprino, Gustavo S França, Joaquim Gama-Rodrigues, Raphael B Parmigiani, Rodrigo O Perez, Pedro AF Galante, Anamaria A Camargo. Comprehensive evaluation of the effectiveness of gene expression signatures to predict complete response to neoadjuvant chemoradiotherapy and guide surgical intervention in rectal cancer.. Cancer genetics. 2015 PubMed PMID: 25963525

Fabio CP Navarro, Pedro AF Galante. A genome-wide landscape of retrocopies in primate genomes. Genome biology and evolution. 2015 PubMed PMID: 26224704

Luís Felipe Campesato, Romualdo Barroso-Sousa, Leandro Jimenez, Bruna R Correa, Jorge Sabbaga, Paulo M Hoff, Luiz FL Reis, Pedro Alexandre F Galante, Anamaria A Camargo. Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice. Oncotarget. 2015 PubMed PMID: 26439694

Paola Carpinetti, Elisa Donnard, Fabiana Bettoni, Paula Asprino, Fernanda Koyama, Andrei Rozanski, Jorge Sabbaga, Angelita Habr-Gama, Raphael B Parmigiani, Pedro AF Galante, Rodrigo O Perez, Anamaria A Camargo. The use of personalized biomarkers and liquid biopsies to monitor treatment response and disease recurrence in locally advanced rectal cancer after neoadjuvant chemoradiation.. Oncotarget. 2015 PubMed PMID: 26451609

FM Cambuli, BR Correa, A Rezza, SC Burns, M Qiao, PJ Uren, E Kress, A Boussouar, PAF Galante, LOF Penalva, M Plateroti. A mouse model of targeted Musashi1 expression in whole intestinal epithelium suggests regulatory roles in cell cycle and stemness. Stem cells. 2015 PubMed PMID: 26303183

Ludwig Christian Hinske, Gustavo S França, Hugo AM Torres, Daniel T Ohara, Camila M Lopes-Ramos, Jens Heyn, Luiz FL Reis, Lucila Ohno-Machado, Simone Kreth, Pedro AF Galante. miRIAD—integrating microRNA inter-and intragenic data. Database. 2014 PubMed PMID: 25288656

Giovana T Torrezan, Elisa N Ferreira, Adriana M Nakahata, Bruna DF Barros, Mayra TM Castro, Bruna R Correa, Ana CV Krepischi, Eloisa HR Olivieri, Isabela W Cunha, Uri Tabori, Paul E Grundy, Cecilia ML Costa, Beatriz De Camargo, Pedro AF Galante, Dirce M Carraro. Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour. Nature communications. 2014 PubMed PMID: 24909261

Elisa Donnard, Paula F Asprino, Bruna R Correa, Fabiana Bettoni, Fernanda C Koyama, Fabio CP Navarro, Rodrigo O Perez, John Mariadason, Oliver M Sieber, Robert L Strausberg, Andrew JG Simpson, Denis LF Jardim, Luiz Fernando L Reis, Raphael B Parmigiani, Pedro AF Galante, Anamaria A Camargo. Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy. Oncotarget. 2014 PubMed PMID: 25193853

Camila Miranda Lopes-Ramos, Angelita Habr-Gama, Bruna de Souza Quevedo, Natália Mariana Felício, Fabiana Bettoni, Fernanda Christtanini Koyama, Paula Fontes Asprino, Pedro Alexandre Galante, Joaquim Gama-Rodrigues, Anamaria Aranha Camargo, Rodrigo Oliva Perez, Raphael Bessa Parmigiani. Overexpression of miR-21-5p as a predictive marker for complete tumor regression to neoadjuvant chemoradiotherapy in rectal cancer patients. BMC medical genomics. 2014 PubMed PMID: 25496125

Ludwig Christian Hinske, Jens Heyn, Pedro AF Galante, Lucila Ohno-Machado, Simone Kreth. Setting up an intronic miRNA database. MicroRNA Protocols. 2013 PubMed PMID: 23007499

Júlia Pinheiro Chagas da Cunha, Pedro Alexandre Favoretto Galante, Jorge Estefano Santana de Souza, Martin Pieprzyk, Dirce Maria Carraro, Lloyd J Old, Anamaria Aranha Camargo, Sandro José de Souza. The human cell surfaceome of breast tumors. BioMed research international. 2013 PubMed PMID: 24195083

Daniel R Schrider, Fabio CP Navarro, Pedro AF Galante, Raphael B Parmigiani, Anamaria A Camargo, Matthew W Hahn, Sandro J de Souza. Gene copy-number polymorphism caused by retrotransposition in humans. PLoS genetics. 2013 PubMed PMID: 23359205

Fábio CP Navarro, Pedro AF Galante. RCPedia: a database of retrocopied genes. Bioinformatics. 2013 PubMed PMID: 23457042

Jorge Estefano Santana de Souza, Pedro Alexandre Favoretto Galante, Renan Valieris Bueno de Almeida, Julia Pinheiro Chagas da Cunha, Daniel Takatori Ohara, Lucila Ohno-Machado, Lloyd J Old, Sandro José de Souza
. SurfaceomeDB: a cancer-orientated database for genes encoding cell surface proteins. Cancer Immunity Archive. 2012 PubMed PMID: 23390370

Célia Regina da Silva Garcia, Bettina Malnic, Luciana Madeira da Silva, Pedro Alexandre Favoretto Galante. Pharmaceutical composition, drug screening method and method for treating malaria. US. 2012 PubMed PMID:

José Eduardo Kroll, Pedro AF Galante, Daniel T Ohara, Fábio CP Navarro, Lucila Ohno-Machado, Sandro J De Souza. SPLOOCE: a new portal for the analysis of human splicing variants. RNA biology. 2012 PubMed PMID: 23064119

Janete M Cerutti, Gisele Oler, Rosana Delcelo, Rene Gerardt, Pedro Michaluart Jr, Sandro J de Souza, Pedro AF Galante, Peng Huang, Gregory J Riggins. PVALB, a new Hurthle adenoma diagnostic marker identified through gene expression. The Journal of Clinical Endocrinology & Metabolism. 2011 PubMed PMID: 20926528

Tainá Raiol, Regina Maria Santos de Amorim, Pedro Galante, Cláudia Renata Fernandes Martins, Luisa Lina Villa, L Sichero. HPV-58 Molecular Variants Exhibit Different Transcriptional Activity. Intervirology. 2011 PubMed PMID: 20948225

Daniel Onofre Vidal DO Vidal, Jorge Estefano S. de Souza JES de Souza, Lilian Campos Pires LC Pires, Cibele Masotti C Masotti, Anna Christina Matos Salim ACM Salim, Maria Cristina Ferreira Costa MCF Costa, Pedro Alexandre Favoretto Galante PAF Galante, Sandro José de Souza SJ de Souza, Anamaria Aranha Camargo AA Camargo. Analysis of allelic differential expression in the human genome using allele-specific serial analysis of gene expression tags.. Genome. 2011 PubMed PMID: 21326368

Jorge ES de Souza, Rodrigo F Ramalho, Pedro AF Galante, Diogo Meyer, Sandro J de Souza. Alternative splicing and genetic diversity: silencers are more frequently modified by SNVs associated with alternative exon/intron borders. Nucleic acids research. 2011 PubMed PMID: 21398627

Pedro AF Galante, Raphael B Parmigiani, Qi Zhao, Otávia L Caballero, Jorge E De Souza, Fábio CP Navarro, Alexandra L Gerber, Marisa F Nicolás, Anna Christina M Salim, Ana Paula M Silva, Lee Edsall, Sylvie Devalle, Luiz G Almeida, Zhen Ye, Samantha Kuan, Daniel G Pinheiro, Israel Tojal, Renato G Pedigoni, Rodrigo GMA De Sousa, Thiago YK Oliveira, Marcelo G De Paula, Lucila Ohno-Machado, Ewen F Kirkness, Samuel Levy, Wilson A Da Silva, Ana Tereza R Vasconcelos, Bing Ren, Marco Antonio Zago, Robert L Strausberg, Andrew JG Simpson, Sandro J De Souza, Anamaria A Camargo. Distinct patterns of somatic alterations in a lymphoblastoid and a tumor genome derived from the same individual. Nucleic acids research. 2011 PubMed PMID: 21493686

M Maschietto, AP Trape, FS Piccoli, TI Ricca, AAM Dias, RA Coudry, PA Galante, C Torres, L Fahhan, S Lourenco, PE Grundy, B De Camargo, S De Souza, EJ Neves, FA Soares, H Brentani, DM Carraro. Temporal blastemal cell gene expression analysis in the kidney reveals new Wnt and related signaling pathway genes to be essential for Wilms\' tumor onset. Cell death & disease. 2011 PubMed PMID: 22048167

Jussara S Michaloski, Pedro AF Galante, Maíra H Nagai, Lucia Armelin-Correa, Ming-Shan Chien, Hiroaki Matsunami, Bettina Malnic. Common promoter elements in odorant and vomeronasal receptor genes. PloS one. 2011 PubMed PMID: 22216168