(Publications from each of our members can be found at their individual pages)


The Bioinformatics Group was created in June 2011. Since then we have been involved in several publications:


Scientific Articles: 25

  • Munford V, Castro LP, Souto R, Lerner LK, Vilar JB, Quayle C, Asif H, Schuch AP, de Souza TA, Ienne S, Alves FI, Moura LM, Galante PA, Camargo AA, Liboredo R, Pena SD, Sarasin A, Chaibub SC, Menck CF. "A genetic cluster of xeroderma pigmentosum variant patients with two different founder mutations". Br J Dermatol. 2016 PubMed PMID: 27664908 (link)


  • Bettoni F, Masotti C, Habr-Gama A, Correa BR, Gama-Rodrigues J, Vianna MR, Vailati BB, São Julião GP, Fernandez LM, Galante PA, Camargo AA, Perez RO. "Intratumoral Genetic Heterogeneity in Rectal Cancer: Are Single Biopsies representative of the entirety of the tumor?". Ann Surg. 2016. PubMed PMID: 27479130 (link)


  • Correa BR, de Araujo PR, Qiao M, Burns SC, Chen C, Schlegel R, Agarwal S, Galante PA, Penalva LO. "Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma". Genome Biol. 2016. PubMed PMID: 27287018 (link)


  • França GS, Vibranovski MD, Galante PA. "Host gene constraints and genomic context impact the expression and evolution of human microRNAs". Nat Commun. 2016. PubMed PMID: 27109497 (link)


  • Guedes EC, França GS, Lino CA, Koyama FC, Moreira Ldo N, Alexandre JG, Barreto-Chaves ML, Galante PA, Diniz GP. "MicroRNA Expression Signature Is Altered in the Cardiac Remodeling Induced by High Fat Diets". J Cell Physiol. 2016. PubMed PMID: 26638879 (link)


  • Guedes EC, França GS, Lino CA, Koyama FC, Moreira LD, Alexandre JG, Barreto-Chaves ML, Galante PA, Diniz GP. "MicroRNA Expression Signature Is Altered in the Cardiac Remodeling Induced by High Fat Diets". J Cell Physiol. 2015 PubMed PMID: 26638879. (link)


  • Carpinetti P, Donnard E, Bettoni F, Asprino P, Koyama F, Rozanski A, Sabbaga J, Habr-Gama A, Parmigiani RB, Galante PA, Perez RO, Camargo AA. The use of personalized biomarkers and liquid biopsies to monitor treatment response and disease recurrence in locally advanced rectal cancer after neoadjuvant chemoradiation. Oncotarget. 2015 PubMed PMID: 26451609. (link)


  • Campesato LF, Barroso-Sousa R, Jimenez L, Correa BR, Sabbaga J, Hoff PM, Reis LF, Galante PA, Camargo AA. Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice. Oncotarget. 2015 PubMed PMID: 26439694. (link)


  • Cambuli FM, Correa BR, Rezza A, Burns SC, Qiao M, Uren PJ, Kress E, Boussouar A, Galante PA, Penalva LO, Plateroti M. A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness. Stem Cells. 2015 Aug 25. doi: 10.1002/stem.2202. PubMed PMID: 26303183. (link)


  • Navarro FC, Galante PA. A genome-wide landscape of retrocopies in primate genomes. Genome Biol Evol. 2015 Jul 29. PubMed PMID: 26224704. (link)


  • Lopes-Ramos C, Koyama FC, Habr-Gama A, Salim AC, Bettoni F, Asprino PF, França GS, Gama-Rodrigues J, Parmigiani RB, Perez RO, Galante PA, Camargo AA. Comprehensive evaluation of the effectiveness of gene expression signatures to predict complete response to neoadjuvant chemoradiotherapy and guide surgical intervention in rectal cancer. Cancer Genet. 2015 Jun;208(6):319-26. doi: 10.1016/j.cancergen.2015.03.010; PubMed PMID: 25963525. (link)


  • Donnard ER, Carpinetti PA, Navarro FC, Perez RO, Habr-Gama A, Parmigiani RB, Camargo AA, Galante PA. ICRmax: An optimized approach to detect tumor-specific interchromosomal rearrangements for clinical application. Genomics. 2015, S0888-7543(15)00027-0. doi: 10.1016/j.ygeno.2015.01.009. (link)


  • Gonzalez-Kristeller D, JBP do Nascimento, PAF Galante, B Malnic. Identification of agonists for a group of human odorant receptors. Frontiers in Pharmacology, 2015 6, 35. (link)


  • Hinske LC, Galante PAF, Limbeck , Parmigiani RB, Heyn J, Schütz S, Ohno-Machado L, Camargo A, Kreth S. Alternative polyadenylation allows differential negative feedback of human miRNA miR-579 on its host gene ZFR. PLOS ONE, 2015. In press.


  • Lopes-Ramos C, Habr-Gama A, Quevedo B, Felício N, Bettoni F, Koyama F, Asprino P, Galante P, Gama-Rodrigues J, Camargo A, Perez R, Parmigiani R. Overexpression of miR-21-5p as a predictive marker for complete tumor regression to neoadjuvant chemoradiotherapy in rectal cancer patients. BMC Med Genomics. 2014, 11;7(1):68. (link)


  • Hinske LC, França GS, Torres HAM, Ohara DT, Lopes-Ramos CM, Heyn J, Reis LFL, Ohno-Machado L, Kreth S, Galante PAF. miRIAD: Integrating microRNA Inter- And Intragenic Data. Database (Oxford). 2014, 6;2014 doi: 10.1093/database/bau099. (link)


  • Donnard E, Asprino PF, Correa BR, Bettoni F, Koyama FC, Navarro FC, Perez RO,  Mariadason J, Sieber OM, Strausberg RL, Simpson AJ, Jardim DL, Reis LF, Parmigiani RB, Galante PA, Camargo AA. Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy. Oncotarget. 2014 (link).


  • Torrezan GT, Ferreira EN, Nakahata AM, Barros BD, Castro MT, Correa BR, Krepischi AC, Olivieri EH, Cunha IW, Tabori U, Grundy PE, Costa CM, de Camargo B, Galante PA, Carraro DM. Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour. Nature Commun. 2014, 5:4039 (link)
  • Navarro FC, Galante PA. RCPedia: a database of retrocopied genes. Bioinformatics. 2013 Mar 25. (link)


  • Schrider DR, Navarro FC, Galante PA, Parmigiani RB, Camargo AA, Hahn MW, de Souza SJ. Gene copy-number polymorphism caused by retrotransposition in humans. PLoS Genet. 2013 Jan;9(1):e1003242. (link)


  • da Cunha JP, Galante PA, de Souza JE, Pieprzyk M, Carraro DM, Old LJ, Camargo AA, de Souza SJ. The human cell surfaceome of breast tumors. Biomed Res Int. 2013:976816 (link)


  • Hinske LC, Heyn J, Galante PAF, Ohno-Machado L, Kreth S. Setting Up an Intronic miRNA Database. Methods Mol Biol. 2013;936:69-76 (link)
  • Kroll JE, Galante PA, Ohara DT, Navarro FC, Ohno-Machado L, de Souza SJ. SPLOOCE: a new portal for the analysis of human splicing variants. RNA Biology. 2012 Nov;9(11):1339-43 (link)


  • de Souza JE, Galante PA, de Almeida RV, da Cunha JP, Ohara DT, Ohno-Machado L, Old LJ, de Souza SJ. SurfaceomeDB: a cancer-orientated database for genes encoding cell surface proteins. Cancer Immun. 2012;12:15 (link)
  • Michaloski JS, Galante PAF, Nagai MH, Armelin-Correa L, Chien M, Matsunami H and Malnic B. Common promoter elements in odorant and vomeronasal receptor genes. PLoS ONE. 2011;6(12):e29065 (link).